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KMID : 0358420120550040269
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Korean Journal of Obstetrics and Gynecology
2012 Volume.55 No. 4 p.269 ~ p.273
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Combined small cell carcinoma and adenocarcinoma arising in uterine cervix
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Lee Hyun-Seung
Moon Young-Jin
Kim Hyun
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Abstract
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We report here on a case of combined small cell carcinoma and adenocarcinoma arising on uterine cervix. The patient was a 39-year-old woman who presented with uterine cervical mass. Colposcopic biopsy confirmed as adenocarcinoma and radical hysterectomy was performed. The mass, measuring in about 2 cm in greatest diameter, was mainly endophytic growing. Histopathologically, the mass was consisted of well differentiated adenocarcinoma from 2 to 9 o’clock directions of uterine cervix. From 9 to 11 o’clock directions, small cell carcinoma was detected. On results of special stain and immunohistochemistry, mucin stains and carcinoembryonic antigen were positive in area of adenocarcinoma. Chromogranin A and synaptophysin, stain for neuroendocrine markers, were positive in region of small cell carcinoma. This case indicates that the small cell carcinoma and adenocarcinoma can simultaneously occur in uterine cervix.
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KEYWORD
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Carcinoma, Small cell, Adenocarcinoma, Cervix Uteri
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